Glycerin 99.7% USP
Glycerin 99.7% USP (United States Pharmacopeia) is a high-purity, colorless,
odorless, and viscous liquid commonly used in pharmaceutical, cosmetic, and
food applications. It is a trihydroxy alcohol (C₃H₈O₃) known for its excellent
humectant, solvent, and emollient properties. In pharmaceuticals, it is widely
used in oral, topical, and parenteral preparations to retain moisture, improve
texture, and enhance solubility. Its purity level of 99.7% makes it suitable
for use in sensitive formulations and ensures compliance with stringent
regulatory standards.
USP Specification for Glycerin 99.7%
- Purity:
Not less than 99.7% w/w (calculated as C₃H₈O₃).
- Appearance:
Clear, colorless, viscous liquid.
- Odor:
Odorless or nearly odorless.
- Identification:
Passes tests for glycerol using infrared absorption or chemical methods.
- Specific
Gravity: Between 1.249 and 1.258 at 25°C.
- Refractive
Index: Between 1.4700 and 1.4750 at 20°C.
- Acidity
or Alkalinity: Passes test (should be neutral to slightly acidic).
- Chlorinated
Compounds: Passes test (limit of chlorinated compounds to ensure
safety).
- Residue
on Ignition: Not more than 0.01%.
- Heavy
Metals: Not more than 5 ppm.
- Diethylene
Glycol and Ethylene Glycol: Must comply with limit tests (typically
<0.1%).
- Water
Content: Typically ≤0.3% (Karl Fischer method).
